Omentin-1 vs Ibutamoren
Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and Ibutamoren (Ibutamoren mesylate (MK-677)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Omentin-1 | Ibutamoren |
|---|---|---|
| Category | Diabetes & Metabolic | Growth Hormone |
| Full Name | Omentin-1 (Intelectin-1, ITLN1) | Ibutamoren mesylate (MK-677) |
| Molecular Weight | ~35 kDa | N/A |
| Half-Life | hours | about 24 hours |
| Amino Acids | 313 | N/A |
| Typical Dose | No approved human dose; research use only | 10-25 mg/day |
| Route | IV|SC | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 82 | 180 |
| Research Status | Pre-clinical | Clinical |
Omentin-1 Benefits
- ✓insulin sensitivity
- ✓glucose uptake
- ✓lipid handling
Ibutamoren Benefits
- ✓raises GH/IGF-1
- ✓increases appetite
- ✓supports lean mass retention
- ✓oral non-peptide secretagogue
Omentin-1 Dosing
not established|not established
Ibutamoren Dosing
10-25 mg orally once daily|take consistently at the same time each day|monitor fasting glucose and edema in longer studies
Omentin-1 Side Effects
- ⚠unknown
- ⚠immunogenicity risk
Ibutamoren Side Effects
- ⚠increased appetite
- ⚠water retention/edema
- ⚠somnolence or lethargy
Research Overview
Omentin-1
Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.
Ibutamoren
Clinical studies show oral ibutamoren reliably elevates GH and IGF-1 over 24 hours with once-daily dosing. Body composition and appetite effects vary by population, and development has been limited by metabolic side effects.
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