Omentin-1 vs Anamorelin
Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and Anamorelin (Anamorelin hydrochloride (ONO-7643)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Omentin-1 | Anamorelin |
|---|---|---|
| Category | Diabetes & Metabolic | Growth Hormone |
| Full Name | Omentin-1 (Intelectin-1, ITLN1) | Anamorelin hydrochloride (ONO-7643) |
| Molecular Weight | ~35 kDa | N/A |
| Half-Life | hours | about 9 hours |
| Amino Acids | 313 | N/A |
| Typical Dose | No approved human dose; research use only | 50 mg/day |
| Route | IV|SC | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 82 | 95 |
| Research Status | Pre-clinical | Clinical |
Omentin-1 Benefits
- ✓insulin sensitivity
- ✓glucose uptake
- ✓lipid handling
Anamorelin Benefits
- ✓stimulates appetite
- ✓raises IGF-1
- ✓may support weight gain
- ✓oral dosing
Omentin-1 Dosing
not established|not established
Anamorelin Dosing
50 mg orally once daily|often studied with food or per protocol|track weight, appetite, and glucose markers
Omentin-1 Side Effects
- ⚠unknown
- ⚠immunogenicity risk
Anamorelin Side Effects
- ⚠hyperglycemia
- ⚠peripheral edema
- ⚠constipation or nausea
Research Overview
Omentin-1
Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.
Anamorelin
Trials in cachexia populations showed increased appetite and modest gains in body weight and IGF-1. Regulatory progress has varied by region, but it remains a well-studied ghrelin agonist in the GH space.
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