Methoxy PEG-Epoetin Beta vs FS315
Head-to-head comparison of Methoxy PEG-Epoetin Beta (Methoxy polyethylene glycol-epoetin beta (CERA)) and FS315 (Follistatin-315 (FS315)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Methoxy PEG-Epoetin Beta | FS315 |
|---|---|---|
| Category | Muscle & Performance | Muscle & Performance |
| Full Name | Methoxy polyethylene glycol-epoetin beta (CERA) | Follistatin-315 (FS315) |
| Molecular Weight | ≈60,000 Da | ~40 kDa |
| Half-Life | ~130 h | N/A; depends on construct/delivery |
| Amino Acids | 165 | 315 |
| Typical Dose | 0.6 mcg/kg SC every 2 weeks or 1.2 mcg/kg SC monthly | Research-only; no standardized human dose |
| Route | Subcutaneous/IV | Intramuscular / research expression systems |
| Purity | ≥98% | ≥98% |
| Studies Count | 95 | 95 |
| Research Status | Clinical | Pre-clinical |
Methoxy PEG-Epoetin Beta Benefits
- ✓long-acting erythropoiesis
- ✓stable hemoglobin
- ✓fewer injections
- ✓improved oxygen delivery
FS315 Benefits
- ✓activin neutralization
- ✓muscle growth signaling
- ✓anti-catabolic support
- ✓tissue repair modulation
Methoxy PEG-Epoetin Beta Dosing
0.6 mcg/kg SC every 2 weeks|1.2 mcg/kg SC monthly|Adjust based on hemoglobin
FS315 Dosing
Research-only recombinant/protein-expression studies|no standardized clinical dose|route varies by platform
Methoxy PEG-Epoetin Beta Side Effects
- ⚠hypertension
- ⚠thromboembolism
- ⚠headache
FS315 Side Effects
- ⚠off-target endocrine effects
- ⚠immune response risk
- ⚠fluid balance changes
Research Overview
Methoxy PEG-Epoetin Beta
Clinical trials show predictable hemoglobin correction with a long dosing interval and sustained red-cell stimulation. Any VO2 max effect would be secondary to higher hemoglobin, not a direct ergogenic mechanism.
FS315
Follistatin-315 is a key reference isoform in studies of muscle anabolism and reproductive/endocrine biology. In muscle research, it is relevant because it suppresses activin and can indirectly blunt myostatin pathway output.
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