GLP-1(7-36) amide vs C-Type Natriuretic Peptide (CNP-22)

Head-to-head comparison of GLP-1(7-36) amide (Glucagon-like peptide-1 (7-36) amide) and C-Type Natriuretic Peptide (CNP-22) (Human C-Type Natriuretic Peptide) — benefits, dosing, side effects, research data, and where to buy.

PropertyGLP-1(7-36) amideC-Type Natriuretic Peptide (CNP-22)
CategoryEndocrine PeptidesEndocrine Peptides
Full NameGlucagon-like peptide-1 (7-36) amideHuman C-Type Natriuretic Peptide
Molecular Weight3297.7 Da~2470 Da
Half-Life1-2 min2-3 min
Amino AcidsHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2SNNLGKQK...N/A
Typical DosepM-nM physiologic range|research-dependentN/A
Routeendogenous secretion|SC/IV in research/clinical analog studiesIV/SC research
Purity≥98%≥98%
Studies Count9985
Research StatusEndogenousEndogenous

GLP-1(7-36) amide Benefits

  • glucose-dependent insulin secretion
  • gastric emptying delay
  • satiety signaling

C-Type Natriuretic Peptide (CNP-22) Benefits

  • cGMP signaling
  • vascular homeostasis
  • endochondral growth

GLP-1(7-36) amide Dosing

physiologic secretion|research-dependent

C-Type Natriuretic Peptide (CNP-22) Dosing

N/A|N/A

GLP-1(7-36) amide Side Effects

  • nausea
  • fullness
  • reduced appetite

C-Type Natriuretic Peptide (CNP-22) Side Effects

  • hypotension
  • headache

Research Overview

GLP-1(7-36) amide

One of the best-studied gut hormones, with strong evidence for incretin biology and appetite regulation. Native GLP-1 is rapidly degraded by DPP-4, which is why its biology is central to endocrine and metabolic pharmacology.

C-Type Natriuretic Peptide (CNP-22)

A real, well-documented natriuretic peptide with strong endocrine/paracrine roles; widely studied for vascular tone, bone growth, and receptor biology.

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Common Stacking Partners

GLP-1(7-36) amide stacks with:

L-cellsinsulinsatiety

C-Type Natriuretic Peptide (CNP-22) stacks with:

NPPCNPR-B
gut-hormoneincretinendocrine-peptidenatriuretic-peptideparacrinecGMP