Ghrelin vs hGHRH(1-40)OH
Head-to-head comparison of Ghrelin (Ghrelin (acylated human ghrelin; endogenous growth hormone secretagogue)) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Ghrelin | hGHRH(1-40)OH |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Ghrelin (acylated human ghrelin; endogenous growth hormone secretagogue) | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | 3367 Da | N/A |
| Half-Life | 20-30 minutes | 5-20 minutes |
| Amino Acids | 28 | 40 |
| Typical Dose | 1-3 mcg/kg | 1-2 mcg/kg |
| Route | Subcutaneous/Intravenous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 2000 | 85 |
| Research Status | Clinical research | Clinical Research |
Ghrelin Benefits
- ✓increases GH pulses
- ✓supports appetite and energy intake
- ✓may support lean mass preservation
- ✓promotes recovery signaling
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
Ghrelin Dosing
1-3 mcg/kg SC or IV|repeat dosing in short research windows|titrate to GH response in monitored studies
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
Ghrelin Side Effects
- ⚠hunger/nausea
- ⚠transient flushing
- ⚠changes in glucose/insulin
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
Ghrelin
Ghrelin is the canonical ligand for the growth hormone secretagogue receptor and is used extensively as a reference compound in GH-axis research. Human and animal studies consistently show rapid, dose-dependent GH release after acyl-ghrelin administration.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
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