Ghrelin vs Capromorelin
Head-to-head comparison of Ghrelin (Ghrelin (acylated human ghrelin; endogenous growth hormone secretagogue)) and Capromorelin (Capromorelin hydrochloride) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Ghrelin | Capromorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Ghrelin (acylated human ghrelin; endogenous growth hormone secretagogue) | Capromorelin hydrochloride |
| Molecular Weight | 3367 Da | N/A |
| Half-Life | 20-30 minutes | about 2-3 hours |
| Amino Acids | 28 | N/A |
| Typical Dose | 1-3 mcg/kg | 0.25-2 mg/kg/day |
| Route | Subcutaneous/Intravenous | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 2000 | 55 |
| Research Status | Clinical research | Clinical |
Ghrelin Benefits
- ✓increases GH pulses
- ✓supports appetite and energy intake
- ✓may support lean mass preservation
- ✓promotes recovery signaling
Capromorelin Benefits
- ✓GH secretagogue activity
- ✓appetite stimulation
- ✓oral administration
- ✓translational animal model utility
Ghrelin Dosing
1-3 mcg/kg SC or IV|repeat dosing in short research windows|titrate to GH response in monitored studies
Capromorelin Dosing
0.25-2 mg/kg orally in studies|once-daily or protocol-specific dosing|monitor appetite and body weight
Ghrelin Side Effects
- ⚠hunger/nausea
- ⚠transient flushing
- ⚠changes in glucose/insulin
Capromorelin Side Effects
- ⚠increased appetite
- ⚠vomiting or nausea
- ⚠lethargy
Research Overview
Ghrelin
Ghrelin is the canonical ligand for the growth hormone secretagogue receptor and is used extensively as a reference compound in GH-axis research. Human and animal studies consistently show rapid, dose-dependent GH release after acyl-ghrelin administration.
Capromorelin
Research consistently shows capromorelin activates the ghrelin receptor pathway and increases food intake. Human development has been less prominent than veterinary use, but the compound remains a relevant GH secretagogue prototype.
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