Capromorelin vs hGHRH(1-40)OH

Head-to-head comparison of Capromorelin (Capromorelin hydrochloride) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyCapromorelinhGHRH(1-40)OH
CategoryGrowth HormoneGrowth Hormone
Full NameCapromorelin hydrochlorideHuman growth hormone-releasing factor (1-40) hydroxyl
Molecular WeightN/AN/A
Half-Lifeabout 2-3 hours5-20 minutes
Amino AcidsN/A40
Typical Dose0.25-2 mg/kg/day1-2 mcg/kg
RouteOralSubcutaneous/IV
Purity≥98%≥98%
Studies Count5585
Research StatusClinicalClinical Research

Capromorelin Benefits

  • GH secretagogue activity
  • appetite stimulation
  • oral administration
  • translational animal model utility

hGHRH(1-40)OH Benefits

  • GH secretion research
  • fragment-activity comparison
  • receptor binding studies
  • axis physiology modeling

Capromorelin Dosing

0.25-2 mg/kg orally in studies|once-daily or protocol-specific dosing|monitor appetite and body weight

hGHRH(1-40)OH Dosing

1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies

Capromorelin Side Effects

  • increased appetite
  • vomiting or nausea
  • lethargy

hGHRH(1-40)OH Side Effects

  • flushing
  • headache
  • lightheadedness

Research Overview

Capromorelin

Research consistently shows capromorelin activates the ghrelin receptor pathway and increases food intake. Human development has been less prominent than veterinary use, but the compound remains a relevant GH secretagogue prototype.

hGHRH(1-40)OH

Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.

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Common Stacking Partners

Capromorelin stacks with:

Nutritional supportResistance training

hGHRH(1-40)OH stacks with:

L-arginineL-ornithineglycine
ghrelin-receptor-agonistappetite-stimulantgh-secretagogueghrhfragmentpituitaryresearch-peptide