Capromorelin vs Macimorelin
Head-to-head comparison of Capromorelin (Capromorelin hydrochloride) and Macimorelin (Macimorelin acetate (AEZS-130)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Capromorelin | Macimorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Capromorelin hydrochloride | Macimorelin acetate (AEZS-130) |
| Molecular Weight | N/A | N/A |
| Half-Life | about 2-3 hours | about 4-6 hours |
| Amino Acids | N/A | N/A |
| Typical Dose | 0.25-2 mg/kg/day | 0.5 mg/kg single oral dose |
| Route | Oral | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 55 | 120 |
| Research Status | Clinical | Clinical |
Capromorelin Benefits
- ✓GH secretagogue activity
- ✓appetite stimulation
- ✓oral administration
- ✓translational animal model utility
Macimorelin Benefits
- ✓diagnostic GH stimulation
- ✓single oral dose
- ✓rapid measurable GH response
- ✓high clinical utility
Capromorelin Dosing
0.25-2 mg/kg orally in studies|once-daily or protocol-specific dosing|monitor appetite and body weight
Macimorelin Dosing
0.5 mg/kg orally as a single dose|fasted testing conditions|serial GH sampling after administration
Capromorelin Side Effects
- ⚠increased appetite
- ⚠vomiting or nausea
- ⚠lethargy
Macimorelin Side Effects
- ⚠dysgeusia or taste disturbance
- ⚠nausea
- ⚠headache
Research Overview
Capromorelin
Research consistently shows capromorelin activates the ghrelin receptor pathway and increases food intake. Human development has been less prominent than veterinary use, but the compound remains a relevant GH secretagogue prototype.
Macimorelin
Macimorelin has been validated in clinical testing as an oral alternative to injectable GH stimulation tests. Its short-term use makes it a useful translational tool for evaluating pituitary GH reserve.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.