Cholecystokinin-8 vs C-Type Natriuretic Peptide (CNP-22)

Head-to-head comparison of Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) and C-Type Natriuretic Peptide (CNP-22) (Human C-Type Natriuretic Peptide) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyCholecystokinin-8C-Type Natriuretic Peptide (CNP-22)
CategoryEndocrine PeptidesEndocrine Peptides
Full NameCholecystokinin (sulfated C-terminal octapeptide, CCK-8)Human C-Type Natriuretic Peptide
Molecular Weight1143.2 Da~2470 Da
Half-Life1-2 min2-3 min
Amino AcidsDY(SO3H)MGWMDF-NH2SNNLGKQK...N/A
Typical Dosephysiologic low-picomolar-nanomolar range|research-dependentN/A
Routeendogenous secretion|research IV/SCIV/SC research
Purity≥98%≥98%
Studies Count9785
Research StatusEndogenousEndogenous

Cholecystokinin-8 Benefits

  • ✓gallbladder contraction
  • ✓pancreatic enzyme release
  • ✓satiety signaling

C-Type Natriuretic Peptide (CNP-22) Benefits

  • ✓cGMP signaling
  • ✓vascular homeostasis
  • ✓endochondral growth

Cholecystokinin-8 Dosing

physiologic secretion|research-dependent

C-Type Natriuretic Peptide (CNP-22) Dosing

N/A|N/A

Cholecystokinin-8 Side Effects

  • ⚠abdominal cramping
  • ⚠nausea
  • ⚠biliary contraction

C-Type Natriuretic Peptide (CNP-22) Side Effects

  • ⚠hypotension
  • ⚠headache

Research Overview

Cholecystokinin-8

CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.

C-Type Natriuretic Peptide (CNP-22)

A real, well-documented natriuretic peptide with strong endocrine/paracrine roles; widely studied for vascular tone, bone growth, and receptor biology.

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Common Stacking Partners

Cholecystokinin-8 stacks with:

gallbladderpancreassatiety

C-Type Natriuretic Peptide (CNP-22) stacks with:

NPPCNPR-B
gut-hormonesatiety-peptideendocrine-peptidenatriuretic-peptideparacrinecGMP