C-peptide vs DSIP
Head-to-head comparison of C-peptide (Connecting peptide (C-peptide)) and DSIP (Delta Sleep-Inducing Peptide) — benefits, dosing, side effects, research data, and where to buy.
| Property | C-peptide | DSIP |
|---|---|---|
| Category | Pain Management | Performance |
| Full Name | Connecting peptide (C-peptide) | Delta Sleep-Inducing Peptide |
| Molecular Weight | 3020.3 Da | 848.8 Da |
| Half-Life | ~20-30 min | ~15-25 minutes |
| Amino Acids | 31 | 9 |
| Typical Dose | no approved analgesic dose|research-only | 100-200 mcg |
| Route | IV|subQ | SC / IV / Intranasal |
| Purity | ≥98% | — |
| Studies Count | 46 | 74 |
| Research Status | Pre-clinical | Pre-clinical |
C-peptide Benefits
- ✓diabetic neuropathy research
- ✓nerve function support
- ✓possible analgesic effect
DSIP Benefits
- ✓Promotes deep delta wave sleep
- ✓Normalizes disrupted sleep patterns
- ✓Reduces cortisol and stress response
- ✓Pain modulating effects
- ✓Antioxidant properties
C-peptide Dosing
0.5-1.0 mg/day in research|route varies by protocol
DSIP Dosing
Standard: 100-200 mcg SC or IV, 30-60 min before bed|Cycle: 10-14 days, 5-7 days off|Chronic insomnia: 100 mcg daily for 2-3 weeks|Can be combined with Ipamorelin pre-bed
C-peptide Side Effects
- ⚠injection-site reactions
- ⚠unknown long-term safety
DSIP Side Effects
- ⚠Common (Mild): Morning grogginess initially, mild headache
- ⚠Rare: Vivid dreams, temporary appetite changes
- ⚠Generally very well tolerated
Research Overview
C-peptide
C-peptide is not an approved analgesic, but multiple studies have examined its effects on peripheral nerve blood flow and neuropathy outcomes. The strongest relevance is in diabetic neuropathic pain rather than migraine.
DSIP
DSIP has moderate clinical evidence from European studies. Human trials show improved sleep quality and normalized sleep-wake cycles. Also studied for alcohol and opiate withdrawal. Unique mechanism distinct from traditional sleep aids.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.