PerformancePre-clinical

DSIP

Delta Sleep-Inducing Peptide

9 Amino Acids · MW: 848.8 Da

Amino Acids

9

Molecular Weight

848.8 Da

Half-life

~15-25 minutes

Research Score

4.2

Studies

74

Storage

N/A

What is DSIP?

DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide that modulates sleep architecture, promoting delta wave (deep) sleep. It also influences stress hormones, pain perception, and has shown antioxidant properties. Originally isolated from rabbit cerebral venous blood.

Key Benefits & Mechanisms

Promotes deep delta wave sleep

Normalizes disrupted sleep patterns

Reduces cortisol and stress response

Pain modulating effects

Antioxidant properties

May improve GH release during sleep

Normalizes blood pressure

Research Summary

DSIP has moderate clinical evidence from European studies. Human trials show improved sleep quality and normalized sleep-wake cycles. Also studied for alcohol and opiate withdrawal. Unique mechanism distinct from traditional sleep aids.