Arenicin-1 vs Trefoil factor 2
Head-to-head comparison of Arenicin-1 (Arenicin-1) and Trefoil factor 2 (Trefoil factor 2 (Spasmolytic Polypeptide)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Arenicin-1 | Trefoil factor 2 |
|---|---|---|
| Category | Marine-Derived | Gastrointestinal |
| Full Name | Arenicin-1 | Trefoil factor 2 (Spasmolytic Polypeptide) |
| Molecular Weight | 2079 Da | ≈11–12 kDa |
| Half-Life | n/a | Unknown |
| Amino Acids | 21 | 106 |
| Typical Dose | n/a | none established |
| Route | preclinical | oral/enteral|research-only |
| Purity | ≥98% | ≥98% |
| Studies Count | 76 | 80 |
| Research Status | Pre-clinical | Pre-clinical |
Arenicin-1 Benefits
- ✓antimicrobial
- ✓anti-biofilm
- ✓membrane-active
Trefoil factor 2 Benefits
- ✓epithelial restitution
- ✓barrier protection
- ✓ulcer healing
Arenicin-1 Dosing
bacterial infection|biofilm disruption
Trefoil factor 2 Dosing
No established clinical dose|preclinical only
Arenicin-1 Side Effects
- ⚠Arenicola marina
Trefoil factor 2 Side Effects
- ⚠limited human data
- ⚠theoretical growth-factor concerns
- ⚠GI discomfort
Research Overview
Arenicin-1
Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.
Trefoil factor 2
TFF2 strengthens mucus-barrier repair and epithelial restitution after gastric injury in experimental systems, making it a well-known gastric-protective peptide.
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Common Stacking Partners
Arenicin-1 stacks with:
Arenicola marinabeta-hairpinantibiotic
Trefoil factor 2 stacks with:
TFF2spasmolytic polypeptide
marine-derivedbioactiveantimicrobial peptidebiofilmgastrointestinalgastric-protectionmucosal-repair