Arenicin-1 vs Larazotide
Head-to-head comparison of Arenicin-1 (Arenicin-1) and Larazotide (Larazotide acetate (AT-1001)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Arenicin-1 | Larazotide |
|---|---|---|
| Category | Marine-Derived | Gastrointestinal |
| Full Name | Arenicin-1 | Larazotide acetate (AT-1001) |
| Molecular Weight | 2079 Da | N/A |
| Half-Life | n/a | short; designed for local gut action |
| Amino Acids | 21 | 8 |
| Typical Dose | n/a | 0.5-4 mg TID (clinical studies) |
| Route | preclinical | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 76 | 40 |
| Research Status | Pre-clinical | Clinical |
Arenicin-1 Benefits
- ✓antimicrobial
- ✓anti-biofilm
- ✓membrane-active
Larazotide Benefits
- ✓tight-junction-support
- ✓reduced-permeability
- ✓symptom-reduction
- ✓barrier-protection
Arenicin-1 Dosing
bacterial infection|biofilm disruption
Larazotide Dosing
0.5-4 mg orally before meals in clinical trials|typically three times daily|short-course or chronic study protocols
Arenicin-1 Side Effects
- ⚠Arenicola marina
Larazotide Side Effects
- ⚠headache
- ⚠nausea
- ⚠abdominal discomfort
Research Overview
Arenicin-1
Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.
Larazotide
Clinical and translational studies suggest larazotide can reduce antigen passage across the epithelium and improve gut barrier function. It is one of the better-known peptides for intestinal permeability and barrier-focused gastrointestinal therapy.
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