Arenicin-1 vs ACE-031
Head-to-head comparison of Arenicin-1 (Arenicin-1) and ACE-031 (ACE-031 (soluble activin receptor type IIB-Fc)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Arenicin-1 | ACE-031 |
|---|---|---|
| Category | Marine-Derived | Muscle & Performance |
| Full Name | Arenicin-1 | ACE-031 (soluble activin receptor type IIB-Fc) |
| Molecular Weight | 2079 Da | ~95 kDa |
| Half-Life | n/a | Days to weeks |
| Amino Acids | 21 | N/A |
| Typical Dose | n/a | 0.1-3 mg/kg in early studies |
| Route | preclinical | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 76 | 75 |
| Research Status | Pre-clinical | Clinical |
Arenicin-1 Benefits
- ✓antimicrobial
- ✓anti-biofilm
- ✓membrane-active
ACE-031 Benefits
- ✓myostatin/activin neutralization
- ✓lean mass gain
- ✓muscle function support
- ✓anti-catabolic effect
Arenicin-1 Dosing
bacterial infection|biofilm disruption
ACE-031 Dosing
Clinical studies used single or repeated SC doses|dose escalation in mg/kg|monitoring for edema/bleeding
Arenicin-1 Side Effects
- ⚠Arenicola marina
ACE-031 Side Effects
- ⚠telangiectasia/vascular effects
- ⚠epistaxis
- ⚠headache/edema
Research Overview
Arenicin-1
Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.
ACE-031
ACE-031 produced increases in lean mass in early studies, but development was curtailed after safety concerns and variable efficacy. Its literature remains important because it validated activin receptor blockade as a muscle-building strategy.
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