Arenicin-1 vs BYM338

Head-to-head comparison of Arenicin-1 (Arenicin-1) and BYM338 (Bimagrumab (BYM338)) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyArenicin-1BYM338
CategoryMarine-DerivedMuscle & Performance
Full NameArenicin-1Bimagrumab (BYM338)
Molecular Weight2079 Da~148 kDa
Half-Lifen/a~2-3 weeks
Amino Acids21N/A
Typical Dosen/a10-30 mg/kg IV in trials
RoutepreclinicalIntravenous
Purity≥98%≥98%
Studies Count76140
Research StatusPre-clinicalClinical

Arenicin-1 Benefits

  • antimicrobial
  • anti-biofilm
  • membrane-active

BYM338 Benefits

  • increased lean mass
  • functional strength support
  • reduced muscle wasting
  • metabolic body-composition shift

Arenicin-1 Dosing

bacterial infection|biofilm disruption

BYM338 Dosing

IV infusion|10-30 mg/kg per study cycle|repeat every 4-12 weeks

Arenicin-1 Side Effects

  • Arenicola marina

BYM338 Side Effects

  • muscle cramps
  • diarrhea/nausea
  • infusion reactions

Research Overview

Arenicin-1

Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.

BYM338

Clinical trials showed meaningful increases in lean mass, with mixed functional outcomes depending on population and endpoint. The antibody remains one of the best-documented receptor-blocking approaches to muscle anabolism in humans.

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Common Stacking Partners

Arenicin-1 stacks with:

Arenicola marinabeta-hairpinantibiotic

BYM338 stacks with:

CreatineVitamin DLeucine
marine-derivedbioactiveantimicrobial peptidebiofilmactrII-blockermonoclonal-antibodysarcopenialean-mass