5-Amino-1MQ vs C-peptide
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and C-peptide (Connecting peptide (C-peptide)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | C-peptide |
|---|---|---|
| Category | Weight Management | Pain Management |
| Full Name | 5-Amino-1-methylquinolinium | Connecting peptide (C-peptide) |
| Molecular Weight | 178.23 g/mol | 3020.3 Da |
| Half-Life | ~6 hours | ~20-30 min |
| Amino Acids | Small molecule | 31 |
| Typical Dose | — | no approved analgesic dose|research-only |
| Route | — | IV|subQ |
| Purity | >98% | ≥98% |
| Studies Count | 28 | 46 |
| Research Status | Active Research | Pre-clinical |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
C-peptide Benefits
- ✓diabetic neuropathy research
- ✓nerve function support
- ✓possible analgesic effect
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
C-peptide Dosing
0.5-1.0 mg/day in research|route varies by protocol
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
C-peptide Side Effects
- ⚠injection-site reactions
- ⚠unknown long-term safety
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
C-peptide
C-peptide is not an approved analgesic, but multiple studies have examined its effects on peripheral nerve blood flow and neuropathy outcomes. The strongest relevance is in diabetic neuropathic pain rather than migraine.
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