5-Amino-1MQ vs Bremelanotide
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | Bremelanotide |
|---|---|---|
| Category | Weight Management | Sexual Health |
| Full Name | 5-Amino-1-methylquinolinium | Bremelanotide (PT-141), cyclic melanocortin receptor agonist |
| Molecular Weight | 178.23 g/mol | 1025.2 Da |
| Half-Life | ~6 hours | about 2.7 h |
| Amino Acids | Small molecule | 7 |
| Typical Dose | — | 1.75 mg |
| Route | — | Subcutaneous |
| Purity | >98% | ≥98% |
| Studies Count | 28 | 200 |
| Research Status | Active Research | Clinical |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
Bremelanotide Benefits
- ✓increases sexual desire
- ✓supports arousal
- ✓may improve erectile response
- ✓on-demand use
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
Bremelanotide Dosing
1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
Bremelanotide Side Effects
- ⚠nausea
- ⚠flushing
- ⚠headache
- ⚠transient blood pressure increase
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
Bremelanotide
Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.