TRH
Thyrotropin-Releasing Hormone
3 Amino Acids · MW: 362.38 Da
Amino Acids
3
Molecular Weight
362.38 Da
Half-life
4-6 minutes
Research Score
4.2
Studies
180
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is TRH?
Thyrotropin-releasing hormone is a tripeptide hormone that also acts within the central nervous system. It has been studied for arousal, memory, and modulation of cholinergic and monoaminergic neurotransmission.
Key Benefits & Mechanisms
alertness
memory consolidation
attention
monoamine modulation
Research Summary
TRH has a long literature in neuropharmacology because it can influence wakefulness and cognition independently of its endocrine role. Rodent and older clinical studies suggest central TRH signaling can alter acetylcholine, dopamine, and related systems involved in learning.
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