Tetracosactide
Tetracosactide (ACTH 1-24, Cosyntropin)
24 Amino Acids · MW: 2933 Da
Amino Acids
24
Molecular Weight
2933 Da
Half-life
~15 minutes
Research Score
4.1
Studies
220
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Tetracosactide?
A synthetic 24-amino-acid fragment of ACTH used as a standard melanocortin probe in research and endocrinology. It retains the N-terminal biological activity relevant to pigment signaling.
Key Benefits & Mechanisms
Melanocortin receptor activation
Supports melanocyte research assays
Useful for adrenal-axis studies
Can inform pigmentation models
Research Summary
Tetracosactide is the synthetic ACTH(1-24) fragment and is commonly used to probe melanocortin receptor signaling. Its melanogenic relevance comes from the same N-terminal motif that drives ACTH-related pigmentation effects.
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