Spexin
Spexin (Neuropeptide NPQ/Spexin-14)
14 Amino Acids · MW: Approximately 1,600 Da
Amino Acids
14
Molecular Weight
Approximately 1,600 Da
Half-life
Minutes to hours
Research Score
4.0
Studies
78
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Spexin?
Spexin is a conserved 14-amino-acid peptide involved in appetite suppression, lipid metabolism, and glucose regulation. It is being studied as a satiety-related signal with potential relevance to obesity and metabolic syndrome.
Key Benefits & Mechanisms
appetite regulation
lipid-metabolism support
glucose-regulation support
energy-balance control
Research Summary
Preclinical experiments show spexin can reduce food intake and influence weight gain in rodents, with effects on hypothalamic feeding circuits and energy balance. Clinical literature is mostly observational, where lower spexin levels often correlate with obesity, insulin resistance, and fatty liver disease.
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