Sermorelin

Growth Hormone Releasing Hormone (1-29)

29 Amino Acids · MW: 3,357.88 Da

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Amino Acids

Molecular Weight

3,357.88 Da

Half-life

~10-20 minutes

Research Score

4.6

Studies

287

Storage

N/A

What is Sermorelin?

Sermorelin is a synthetic analog of the first 29 amino acids of GHRH. Previously FDA-approved as Geref for pediatric GH deficiency, it stimulates natural, pulsatile GH release from the pituitary. Widely used in anti-aging medicine for its physiological approach to GH optimization.

Key Benefits & Mechanisms

Stimulates natural GH release

Maintains pulsatile GH secretion

Improved deep sleep quality

Enhanced body composition

Anti-aging effects

Does not suppress pituitary function

FDA-approved safety track record

Research Summary

Sermorelin was FDA-approved (Geref) and has a strong clinical safety record. Discontinued commercially but remains widely used in compounding. Extensive clinical data supports efficacy for GH stimulation with a physiological release pattern.

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