What is Sermorelin?
Sermorelin is a synthetic analog of the first 29 amino acids of GHRH. Previously FDA-approved as Geref for pediatric GH deficiency, it stimulates natural, pulsatile GH release from the pituitary. Widely used in anti-aging medicine for its physiological approach to GH optimization.
Key Benefits & Mechanisms
Stimulates natural GH release
Maintains pulsatile GH secretion
Improved deep sleep quality
Enhanced body composition
Anti-aging effects
Does not suppress pituitary function
FDA-approved safety track record
Research Summary
Sermorelin was FDA-approved (Geref) and has a strong clinical safety record. Discontinued commercially but remains widely used in compounding. Extensive clinical data supports efficacy for GH stimulation with a physiological release pattern.