Pramlintide

Pramlintide Acetate

37 aa Amino Acids · MW: 3949.42 Da

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Amino Acids

37 aa

Molecular Weight

3949.42 Da

Half-life

Approximately 48 minutes

Research Score

4.4

Studies

250

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Pramlintide?

Pramlintide is a synthetic amylin analog that slows gastric emptying, suppresses post-meal glucagon, and increases satiety. It is one of the best-studied peptide options for reducing meal size and supporting modest weight loss.

Key Benefits & Mechanisms

increased satiety

reduced caloric intake

postprandial glucose control

modest weight loss

Research Summary

Pramlintide has been evaluated in multiple diabetes and obesity studies, where it consistently reduces food intake and body weight. Its weight-loss effect is modest but reproducible, especially when paired with structured lifestyle intervention.

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