Pegylated Mechano Growth Factor
PEG-MGF (Pegylated IGF-1Ec)
24 Amino Acids · MW: ~5,000 Da (with PEG)
Amino Acids
24
Molecular Weight
~5,000 Da (with PEG)
Half-life
~several hours (PEG extends)
Research Score
4.1
Studies
45
Storage
N/A
What is Pegylated Mechano Growth Factor?
PEG-MGF is a pegylated form of Mechano Growth Factor, a splice variant of IGF-1 that is released in response to mechanical stress on muscle tissue. The PEG modification extends its half-life from minutes to hours. It activates satellite cells for muscle repair and hyperplasia.
Key Benefits & Mechanisms
Activates muscle satellite cells
Promotes muscle repair and hyperplasia
Extended half-life vs native MGF
Enhanced recovery from training
Local muscle growth at injection site
Promotes new muscle fiber formation
Complementary to IGF-1 LR3
Research Summary
PEG-MGF has moderate pre-clinical evidence. Studies demonstrate satellite cell activation and muscle repair. The pegylated form shows improved pharmacokinetics over native MGF. Human clinical data is limited but anecdotal reports are positive for recovery.
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