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PerformancePre-clinical

Pegylated Mechano Growth Factor

PEG-MGF (Pegylated IGF-1Ec)

24 Amino Acids · MW: ~5,000 Da (with PEG)

Amino Acids

24

Molecular Weight

~5,000 Da (with PEG)

Half-life

~several hours (PEG extends)

Research Score

4.1

Studies

45

Storage

N/A

What is Pegylated Mechano Growth Factor?

PEG-MGF is a pegylated form of Mechano Growth Factor, a splice variant of IGF-1 that is released in response to mechanical stress on muscle tissue. The PEG modification extends its half-life from minutes to hours. It activates satellite cells for muscle repair and hyperplasia.

Key Benefits & Mechanisms

Activates muscle satellite cells

Promotes muscle repair and hyperplasia

Extended half-life vs native MGF

Enhanced recovery from training

Local muscle growth at injection site

Promotes new muscle fiber formation

Complementary to IGF-1 LR3

Research Summary

PEG-MGF has moderate pre-clinical evidence. Studies demonstrate satellite cell activation and muscle repair. The pegylated form shows improved pharmacokinetics over native MGF. Human clinical data is limited but anecdotal reports are positive for recovery.