Nesfatin-1
Nesfatin-1 (NUCB2-Derived Peptide)
82 Amino Acids · MW: Approximately 9,300 Da
Amino Acids
82
Molecular Weight
Approximately 9,300 Da
Half-life
Minutes to hours; not well established
Research Score
4.2
Studies
110
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Nesfatin-1?
Nesfatin-1 is an anorexigenic peptide derived from nucleobindin-2 and is implicated in satiety, energy balance, and glucose regulation. It is widely cited in obesity research because it appears to suppress feeding in several experimental models.
Key Benefits & Mechanisms
satiety signaling
food-intake reduction
energy-balance regulation
glucose-homeostasis support
Research Summary
Preclinical work shows nesfatin-1 can reduce food intake and influence body-weight gain via hypothalamic feeding circuits. Clinical literature is mostly observational, with lower circulating levels often reported in obesity and insulin resistance.
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