Kisspeptin-10
Metastin 45-54 (KiSS-1 Fragment)
10 Amino Acids · MW: 1,302.41 Da
Amino Acids
10
Molecular Weight
1,302.41 Da
Half-life
~4 minutes
Research Score
4.3
Studies
156
Storage
N/A
What is Kisspeptin-10?
Kisspeptin-10 is a fragment of the kisspeptin hormone that plays a master regulatory role in the hypothalamic-pituitary-gonadal (HPG) axis. It triggers the release of GnRH, which stimulates LH and FSH production, making it a powerful natural testosterone stimulator without suppression.
Key Benefits & Mechanisms
Stimulates natural testosterone production
Activates GnRH release
Increases LH and FSH
Does not suppress HPG axis
May restore fertility
Supports post-cycle recovery
Natural hormone optimization
Research Summary
Kisspeptin-10 has growing clinical evidence. Multiple human studies demonstrate reliable GnRH stimulation and subsequent testosterone increase. Being actively studied for reproductive medicine, including IVF protocols and hypogonadism. Unique advantage of not suppressing the HPG axis.
Related Peptides
Ipamorelin
Growth Hormone Secretagogue
Ipamorelin is a selective growth hormone secretagogue that stimulates natural GH release without significantly affecting cortisol or prolactin levels. It is considered one of the safest and most selective GHRPs available.
PerformanceCJC-1295
Growth Hormone Releasing Hormone Analog
CJC-1295 is a modified GHRH analog with an extended half-life due to Drug Affinity Complex (DAC) technology. It promotes sustained, pulsatile GH release, improving body composition, recovery, and sleep quality.
PerformanceGHRP-6
Growth Hormone Releasing Peptide-6
GHRP-6 is a hexapeptide that stimulates the ghrelin receptor to promote growth hormone release. It is one of the earliest and most studied GH secretagogues, known for significant GH pulse induction and appetite stimulation.
PerformanceIGF-1 LR3
Insulin-like Growth Factor-1 Long R3
IGF-1 LR3 is a modified version of IGF-1 with 13 times the half-life of native IGF-1. It promotes anabolic signaling, muscle hyperplasia, and cellular repair with extended bioavailability.
Performance