RenalPre-clinical
Glutathione
gamma-L-glutamyl-L-cysteinylglycine
3 Amino Acids · MW: 307.32
Amino Acids
3
Molecular Weight
307.32
Half-life
minutes
Research Score
4.3
Studies
84
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Glutathione?
Endogenous tripeptide and major intracellular thiol antioxidant. Renal studies show protection against cisplatin, ischemia-reperfusion, and contrast-related oxidative injury.
Key Benefits & Mechanisms
redox support
antioxidant
tubular protection
Research Summary
Glutathione replenishment has been explored to limit oxidative damage in proximal tubules and preserve mitochondrial function after nephrotoxic exposures. Benefits are largely tied to restoring the GSH/GSSG balance rather than a receptor-mediated effect.