Apelin-13
Apelin-13, Active Apelin Isoform
13 Amino Acids · MW: Approximately 1,500 Da
Amino Acids
13
Molecular Weight
Approximately 1,500 Da
Half-life
Minutes
Research Score
4.1
Studies
120
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Apelin-13?
Apelin-13 is a biologically active apelin fragment that signals through the APJ receptor and influences glucose utilization, adipose biology, and vascular function. It is studied as a metabolic peptide because its signaling can alter energy expenditure and body-composition pathways.
Key Benefits & Mechanisms
glucose-uptake modulation
adipose-tissue signaling
thermogenesis support
metabolic regulation
Research Summary
Apelin signaling has been tested in rodent obesity models, where it can alter adiposity, insulin action, and brown-fat thermogenesis. Human studies associate apelin dysregulation with obesity and type 2 diabetes, but therapeutic translation remains early.
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