Thymalin vs Thymopentin
Head-to-head comparison of Thymalin (Calf Thymus Peptide Fraction (Thymalin)) and Thymopentin (L-Arginyl-L-Lysyl-L-Aspartyl-L-Valyl-L-Tyrosine) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Thymalin | Thymopentin |
|---|---|---|
| Category | Immune Support | Immune Support |
| Full Name | Calf Thymus Peptide Fraction (Thymalin) | L-Arginyl-L-Lysyl-L-Aspartyl-L-Valyl-L-Tyrosine |
| Molecular Weight | N/A | 676.78 Da |
| Half-Life | N/A | 10-30 min |
| Amino Acids | N/A | 5 |
| Typical Dose | 5-20 mg | 1 mg |
| Route | Intramuscular | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 120 | 90 |
| Research Status | Clinical | Clinical |
Thymalin Benefits
- ✓t-cell support
- ✓leukocyte recovery
- ✓immunomodulation
- ✓infection-resilience
Thymopentin Benefits
- ✓t-cell maturation
- ✓helper-suppressor balance
- ✓immune recovery
- ✓antiviral-adjunct research
Thymalin Dosing
5-10 mg IM daily|3-10 day cycles|repeat cycles after 1-4 weeks if studied
Thymopentin Dosing
1 mg SC or IM|2-3x weekly|4-8 week study cycles
Thymalin Side Effects
- ⚠injection-site discomfort
- ⚠transient fever
- ⚠rash/allergy
Thymopentin Side Effects
- ⚠injection-site redness
- ⚠mild fever
- ⚠headache
Research Overview
Thymalin
Thymalin appears in Soviet/Russian clinical literature as a thymus peptide complex used to normalize immune parameters after illness, surgery, or radiation exposure. Reports commonly focus on changes in lymphocyte subsets, phagocytic activity, and infection frequency rather than a single isolated peptide mechanism.
Thymopentin
Thymopentin has a long history of preclinical and clinical investigation as a thymic peptide immunomodulator. Published studies report effects on T-cell subsets, cytokine responses, and immune recovery in recurrent infection settings.
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