Thymalin vs Pidotimod
Head-to-head comparison of Thymalin (Calf Thymus Peptide Fraction (Thymalin)) and Pidotimod (3-L-Pyroglutamyl-L-Thiazolidine-4-Carboxylic Acid) — benefits, dosing, side effects, research data, and where to buy.
| Property | Thymalin | Pidotimod |
|---|---|---|
| Category | Immune Support | Immune Support |
| Full Name | Calf Thymus Peptide Fraction (Thymalin) | 3-L-Pyroglutamyl-L-Thiazolidine-4-Carboxylic Acid |
| Molecular Weight | N/A | 244.27 Da |
| Half-Life | N/A | 3-4 h |
| Amino Acids | N/A | 2 |
| Typical Dose | 5-20 mg | 400-800 mg/day |
| Route | Intramuscular | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 120 | 200 |
| Research Status | Clinical | Clinical |
Thymalin Benefits
- ✓t-cell support
- ✓leukocyte recovery
- ✓immunomodulation
- ✓infection-resilience
Pidotimod Benefits
- ✓oral-immune-support
- ✓respiratory-infection-adjunct
- ✓innate-immunity
- ✓adaptive-immunity-support
Thymalin Dosing
5-10 mg IM daily|3-10 day cycles|repeat cycles after 1-4 weeks if studied
Pidotimod Dosing
400 mg PO BID|typically 15-30 days|repeated seasonal cycles in studies
Thymalin Side Effects
- ⚠injection-site discomfort
- ⚠transient fever
- ⚠rash/allergy
Pidotimod Side Effects
- ⚠nausea
- ⚠diarrhea
- ⚠rash
Research Overview
Thymalin
Thymalin appears in Soviet/Russian clinical literature as a thymus peptide complex used to normalize immune parameters after illness, surgery, or radiation exposure. Reports commonly focus on changes in lymphocyte subsets, phagocytic activity, and infection frequency rather than a single isolated peptide mechanism.
Pidotimod
Pidotimod has human data in recurrent infections, especially where immune stimulation or reduced infection frequency is the target. Published work commonly reports improvements in phagocyte function, mucosal defense, and fewer respiratory infection episodes.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.