Tesofensine vs hGHRH(1-37)OH
Head-to-head comparison of Tesofensine (Tesofensine (NS2330)) and hGHRH(1-37)OH (Human growth hormone-releasing factor (1-37) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Tesofensine | hGHRH(1-37)OH |
|---|---|---|
| Category | Weight Management | Growth Hormone |
| Full Name | Tesofensine (NS2330) | Human growth hormone-releasing factor (1-37) hydroxyl |
| Molecular Weight | 426.52 g/mol | N/A |
| Half-Life | ~200-300 hours | 5-20 minutes |
| Amino Acids | Small molecule | 37 |
| Typical Dose | — | 1-2 mcg/kg |
| Route | — | Subcutaneous/IV |
| Purity | >98% | ≥98% |
| Studies Count | 35 | 60 |
| Research Status | Phase III Clinical Trials | Clinical Research |
Tesofensine Benefits
- ✓Potent appetite suppression, increased metabolic rate, enhanced thermogenesis, improved mood during dieting, reduces food reward-seeking behavior
hGHRH(1-37)OH Benefits
- ✓GH release studies
- ✓minimal-sequence mapping
- ✓receptor pharmacology
- ✓peptide stability research
Tesofensine Dosing
Clinical doses: 0.25-1.0 mg orally once daily. Research typically uses 0.5 mg. Extremely long half-life (8-13 days) means steady-state in 7-10 days.
hGHRH(1-37)OH Dosing
1-2 mcg/kg SC or IV bolus|acute stimulation with serial GH assays|short-course research administration with biomarker monitoring
Tesofensine Side Effects
- ⚠Dry mouth, insomnia, constipation, increased heart rate, elevated blood pressure. Not recommended with uncontrolled hypertension.
hGHRH(1-37)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient fatigue
Research Overview
Tesofensine
Phase II trials showed 12.8 kg average weight loss at 1.0 mg dose over 6 months. Simultaneously inhibits reuptake of norepinephrine, dopamine, and serotonin, producing appetite suppression and increased thermogenesis.
hGHRH(1-37)OH
Human GHRF(1-37)OH has appeared in studies examining how loss of C-terminal residues affects biological activity at the GHRH receptor. It is often used alongside other fragments to define structure-activity relationships within the GHRH family.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.