Secretin vs Noopept

Head-to-head comparison of Secretin (Human Secretin) and Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertySecretinNoopept
CategoryGastrointestinalCognitive Enhancement
Full NameHuman SecretinN-phenylacetyl-L-prolylglycine ethyl ester
Molecular Weight3055.4 Da318.37 Da
Half-Life5-7 minutes20-30 minutes
Amino Acids27N/A
Typical Dose0.2 mcg/kg IV10-30 mg/day
RouteIntravenousOral
Purity≥98%≥98%
Studies Count80060
Research StatusClinicalClinical

Secretin Benefits

  • stimulates-pancreatic-secretion
  • supports-bicarbonate-release
  • aids-duodenal-pH-control
  • helps-digestive-coordination

Noopept Benefits

  • memory recall
  • learning efficiency
  • attention support
  • neurotrophic signaling

Secretin Dosing

0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration

Noopept Dosing

oral research use|10-30 mg per day in human studies|divided or single daily dosing

Secretin Side Effects

  • flushing
  • nausea
  • abdominal-cramping

Noopept Side Effects

  • headache
  • irritability
  • sleep disturbance

Research Overview

Secretin

Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.

Noopept

Noopept has been reported to increase NGF/BDNF-related signaling and improve performance in tasks involving learning and recall. Evidence includes preclinical studies and small human studies, but the overall literature is still modest compared with mainstream cognitive drugs.

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Common Stacking Partners

Secretin stacks with:

pancreatic-enzymesacid-controlmeal-timing

Noopept stacks with:

gpedavunetidedesmopressin
pancreatic-secretionbicarbonateduodenal-hormonedigestionpeptide-derivednootropicmemory