Secretin vs GHRP-2
Head-to-head comparison of Secretin (Human Secretin) and GHRP-2 (Growth Hormone Releasing Peptide-2) — benefits, dosing, side effects, research data, and where to buy.
| Property | Secretin | GHRP-2 |
|---|---|---|
| Category | Gastrointestinal | Performance |
| Full Name | Human Secretin | Growth Hormone Releasing Peptide-2 |
| Molecular Weight | 3055.4 Da | 817.97 Da |
| Half-Life | 5-7 minutes | ~25 minutes |
| Amino Acids | 27 | 6 |
| Typical Dose | 0.2 mcg/kg IV | 100-300 mcg |
| Route | Intravenous | SC / IV |
| Purity | ≥98% | — |
| Studies Count | 800 | 172 |
| Research Status | Clinical | Approved (Japan) |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
GHRP-2 Benefits
- ✓Potent GH release (stronger than GHRP-6)
- ✓Less appetite stimulation than GHRP-6
- ✓Improved body composition
- ✓Enhanced deep sleep quality
- ✓Cytoprotective properties
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
GHRP-2 Dosing
Standard: 100-300 mcg SC 2-3 times daily|Pre-bed: 100-200 mcg for GH pulse during sleep|Combined: 100 mcg with CJC-1295 for synergy|Cycle: 8-16 weeks, 4 weeks off
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
GHRP-2 Side Effects
- ⚠Common: Mild appetite increase, water retention, tingling
- ⚠Moderate: Cortisol elevation at higher doses
- ⚠Rare: Prolactin increase, transient dizziness
- ⚠Better tolerated than GHRP-6 overall
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
GHRP-2
GHRP-2 has strong clinical evidence. Approved in Japan for diagnostic use. Multiple human studies confirm reliable GH stimulation with a favorable side effect profile compared to GHRP-6.
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