Secretin vs hGHRH(1-44)
Head-to-head comparison of Secretin (Human Secretin) and hGHRH(1-44) (Human growth hormone-releasing hormone (1-44) amide) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Secretin | hGHRH(1-44) |
|---|---|---|
| Category | Gastrointestinal | Growth Hormone |
| Full Name | Human Secretin | Human growth hormone-releasing hormone (1-44) amide |
| Molecular Weight | 3055.4 Da | N/A |
| Half-Life | 5-7 minutes | 5-15 minutes |
| Amino Acids | 27 | 44 |
| Typical Dose | 0.2 mcg/kg IV | 0.1-1 mcg/kg |
| Route | Intravenous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 800 | 120 |
| Research Status | Clinical | Clinical Research |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
hGHRH(1-44) Benefits
- ✓physiologic GH pulse support
- ✓IGF-1 pathway stimulation
- ✓pituitary receptor mapping
- ✓endocrine research tool
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
hGHRH(1-44) Dosing
0.1-1 mcg/kg SC or IV bolus for stimulation studies|single-dose endocrine challenge with timed GH sampling|pulsatile administration in clamp/infusion experiments
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
hGHRH(1-44) Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient nausea
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
hGHRH(1-44)
Human GHRH(1-44) amide has been used extensively to characterize hypothalamic control of pituitary somatotrophs and the downstream GH/IGF-1 axis. It remains a standard comparator in studies of GHRH agonism, secretion dynamics, and receptor pharmacology.
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