Omentin-1 vs NGF
Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and NGF (Beta-Nerve Growth Factor (human NGF beta)) — benefits, dosing, side effects, research data, and where to buy.
| Property | Omentin-1 | NGF |
|---|---|---|
| Category | Diabetes & Metabolic | Cognitive Enhancement |
| Full Name | Omentin-1 (Intelectin-1, ITLN1) | Beta-Nerve Growth Factor (human NGF beta) |
| Molecular Weight | ~35 kDa | 13,600 Da |
| Half-Life | hours | hours |
| Amino Acids | 313 | 118 aa |
| Typical Dose | No approved human dose; research use only | research-only microgram range |
| Route | IV|SC | Intranasal |
| Purity | ≥98% | ≥98% |
| Studies Count | 82 | 3500 |
| Research Status | Pre-clinical | Pre-clinical |
Omentin-1 Benefits
- ✓insulin sensitivity
- ✓glucose uptake
- ✓lipid handling
NGF Benefits
- ✓neurite outgrowth
- ✓cholinergic support
- ✓nerve repair
- ✓neuroprotection
Omentin-1 Dosing
not established|not established
NGF Dosing
0.01-1 µg/kg in experimental delivery studies|local CNS or intranasal research delivery|single or repeated low-dose protocols
Omentin-1 Side Effects
- ⚠unknown
- ⚠immunogenicity risk
NGF Side Effects
- ⚠pain at injection site
- ⚠hyperalgesia
- ⚠autonomic effects
Research Overview
Omentin-1
Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.
NGF
NGF is one of the most established growth factors in neurobiology and has been investigated for both central and peripheral neuronal repair. Its strongest cognitive relevance comes from supporting basal forebrain cholinergic neurons and downstream memory circuitry.
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