Insulin Aspart vs Insulin Lispro
Head-to-head comparison of Insulin Aspart (Insulin aspart (B28-Asp human insulin analog)) and Insulin Lispro (Insulin lispro (B28-Lys, B29-Pro human insulin analog)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Insulin Aspart | Insulin Lispro |
|---|---|---|
| Category | Diabetes & Metabolic | Diabetes & Metabolic |
| Full Name | Insulin aspart (B28-Asp human insulin analog) | Insulin lispro (B28-Lys, B29-Pro human insulin analog) |
| Molecular Weight | 5825.8 Da | 5808.0 Da |
| Half-Life | About 1-3 hours | About 1 hour |
| Amino Acids | 51 | 51 |
| Typical Dose | 0.05-0.2 U/kg per meal | 0.05-0.2 U/kg per meal |
| Route | Subcutaneous | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 11000 | 12000 |
| Research Status | Approved | Approved |
Insulin Aspart Benefits
- ✓Fast post-meal glucose lowering
- ✓Predictable onset
- ✓Flexible mealtime administration
- ✓Compatible with pump therapy
Insulin Lispro Benefits
- ✓Rapid postprandial glucose control
- ✓Flexible premeal timing
- ✓Predictable onset of action
- ✓Useful in basal-bolus regimens
Insulin Aspart Dosing
Inject SC immediately before meals|Titrate using glucose monitoring and carbohydrate intake|Can be used in insulin pumps or basal-bolus regimens
Insulin Lispro Dosing
Inject SC 0-15 minutes before meals|Adjust dose to carbohydrate intake and premeal glucose|Often paired with a basal insulin
Insulin Aspart Side Effects
- ⚠Hypoglycemia
- ⚠Injection-site reactions
- ⚠Weight gain
Insulin Lispro Side Effects
- ⚠Hypoglycemia
- ⚠Weight gain
- ⚠Injection-site reactions
Research Overview
Insulin Aspart
Research consistently shows faster onset and earlier peak action than regular human insulin. It is commonly studied for meal-time glycemic control and pump-based insulin delivery.
Insulin Lispro
Clinical studies show faster onset and shorter duration than regular insulin, improving post-meal glucose control. It is a standard comparator in diabetes pharmacology and closed-loop insulin-delivery research.
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