HGH Fragment 176-191 vs Cholecystokinin-8
Head-to-head comparison of HGH Fragment 176-191 (Human Growth Hormone Fragment 176-191) and Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | HGH Fragment 176-191 | Cholecystokinin-8 |
|---|---|---|
| Category | Weight Management | Endocrine Peptides |
| Full Name | Human Growth Hormone Fragment 176-191 | Cholecystokinin (sulfated C-terminal octapeptide, CCK-8) |
| Molecular Weight | 1817.12 g/mol | 1143.2 Da |
| Half-Life | ~30 minutes | 1-2 min |
| Amino Acids | 16 | DY(SO3H)MGWMDF-NH2 |
| Typical Dose | — | physiologic low-picomolar-nanomolar range|research-dependent |
| Route | — | endogenous secretion|research IV/SC |
| Purity | >98% | ≥98% |
| Studies Count | 45 | 97 |
| Research Status | Active Research | Endogenous |
HGH Fragment 176-191 Benefits
- ✓Targeted fat loss, no blood sugar impact, no IGF-1 elevation, inhibits lipogenesis, stimulates lipolysis, improved body composition
Cholecystokinin-8 Benefits
- ✓gallbladder contraction
- ✓pancreatic enzyme release
- ✓satiety signaling
HGH Fragment 176-191 Dosing
250-500 mcg subcutaneously 1-2 times daily on empty stomach. 12-16 week cycles typical in research.
Cholecystokinin-8 Dosing
physiologic secretion|research-dependent
HGH Fragment 176-191 Side Effects
- ⚠Injection site irritation, headache, drowsiness. Does not affect blood sugar, insulin sensitivity, or elevate IGF-1.
Cholecystokinin-8 Side Effects
- ⚠abdominal cramping
- ⚠nausea
- ⚠biliary contraction
Research Overview
HGH Fragment 176-191
This 16-amino-acid fragment specifically targets adipose tissue via beta-3 adrenergic receptors. Works through a GH-receptor-independent pathway, explaining selective fat-loss properties without growth-promoting effects.
Cholecystokinin-8
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
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