HGH Fragment 176-191 vs Bremelanotide
Head-to-head comparison of HGH Fragment 176-191 (Human Growth Hormone Fragment 176-191) and Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | HGH Fragment 176-191 | Bremelanotide |
|---|---|---|
| Category | Weight Management | Sexual Health |
| Full Name | Human Growth Hormone Fragment 176-191 | Bremelanotide (PT-141), cyclic melanocortin receptor agonist |
| Molecular Weight | 1817.12 g/mol | 1025.2 Da |
| Half-Life | ~30 minutes | about 2.7 h |
| Amino Acids | 16 | 7 |
| Typical Dose | — | 1.75 mg |
| Route | — | Subcutaneous |
| Purity | >98% | ≥98% |
| Studies Count | 45 | 200 |
| Research Status | Active Research | Clinical |
HGH Fragment 176-191 Benefits
- ✓Targeted fat loss, no blood sugar impact, no IGF-1 elevation, inhibits lipogenesis, stimulates lipolysis, improved body composition
Bremelanotide Benefits
- ✓increases sexual desire
- ✓supports arousal
- ✓may improve erectile response
- ✓on-demand use
HGH Fragment 176-191 Dosing
250-500 mcg subcutaneously 1-2 times daily on empty stomach. 12-16 week cycles typical in research.
Bremelanotide Dosing
1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours
HGH Fragment 176-191 Side Effects
- ⚠Injection site irritation, headache, drowsiness. Does not affect blood sugar, insulin sensitivity, or elevate IGF-1.
Bremelanotide Side Effects
- ⚠nausea
- ⚠flushing
- ⚠headache
- ⚠transient blood pressure increase
Research Overview
HGH Fragment 176-191
This 16-amino-acid fragment specifically targets adipose tissue via beta-3 adrenergic receptors. Works through a GH-receptor-independent pathway, explaining selective fat-loss properties without growth-promoting effects.
Bremelanotide
Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.
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