hGHRH(1-32)NH2 vs Capromorelin
Head-to-head comparison of hGHRH(1-32)NH2 (Human growth hormone-releasing factor (1-32) amide) and Capromorelin (Capromorelin hydrochloride) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | hGHRH(1-32)NH2 | Capromorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Human growth hormone-releasing factor (1-32) amide | Capromorelin hydrochloride |
| Molecular Weight | N/A | N/A |
| Half-Life | 5-15 minutes | about 2-3 hours |
| Amino Acids | 32 | N/A |
| Typical Dose | 0.1-1 mcg/kg | 0.25-2 mg/kg/day |
| Route | Subcutaneous/IV | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 50 | 55 |
| Research Status | Clinical Research | Clinical |
hGHRH(1-32)NH2 Benefits
- ✓GH pulse induction
- ✓core-sequence testing
- ✓receptor signaling studies
- ✓protease-resistance comparisons
Capromorelin Benefits
- ✓GH secretagogue activity
- ✓appetite stimulation
- ✓oral administration
- ✓translational animal model utility
hGHRH(1-32)NH2 Dosing
0.1-1 mcg/kg SC or IV bolus|acute GH-response testing with timed blood draws|pulsatile dosing in receptor studies
Capromorelin Dosing
0.25-2 mg/kg orally in studies|once-daily or protocol-specific dosing|monitor appetite and body weight
hGHRH(1-32)NH2 Side Effects
- ⚠headache
- ⚠flushing
- ⚠injection-site irritation
Capromorelin Side Effects
- ⚠increased appetite
- ⚠vomiting or nausea
- ⚠lethargy
Research Overview
hGHRH(1-32)NH2
Human GHRF(1-32)NH2 is used in basic and translational studies to evaluate how the active N-terminal region of GHRH drives pituitary hormone release. It helps define the lower bound of sequence length needed for meaningful biological activity.
Capromorelin
Research consistently shows capromorelin activates the ghrelin receptor pathway and increases food intake. Human development has been less prominent than veterinary use, but the compound remains a relevant GH secretagogue prototype.
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