Bremelanotide vs hGHRH(1-37)OH
Head-to-head comparison of Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) and hGHRH(1-37)OH (Human growth hormone-releasing factor (1-37) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Bremelanotide | hGHRH(1-37)OH |
|---|---|---|
| Category | Sexual Health | Growth Hormone |
| Full Name | Bremelanotide (PT-141), cyclic melanocortin receptor agonist | Human growth hormone-releasing factor (1-37) hydroxyl |
| Molecular Weight | 1025.2 Da | N/A |
| Half-Life | about 2.7 h | 5-20 minutes |
| Amino Acids | 7 | 37 |
| Typical Dose | 1.75 mg | 1-2 mcg/kg |
| Route | Subcutaneous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 200 | 60 |
| Research Status | Clinical | Clinical Research |
Bremelanotide Benefits
- ✓increases sexual desire
- ✓supports arousal
- ✓may improve erectile response
- ✓on-demand use
hGHRH(1-37)OH Benefits
- ✓GH release studies
- ✓minimal-sequence mapping
- ✓receptor pharmacology
- ✓peptide stability research
Bremelanotide Dosing
1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours
hGHRH(1-37)OH Dosing
1-2 mcg/kg SC or IV bolus|acute stimulation with serial GH assays|short-course research administration with biomarker monitoring
Bremelanotide Side Effects
- ⚠nausea
- ⚠flushing
- ⚠headache
- ⚠transient blood pressure increase
hGHRH(1-37)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient fatigue
Research Overview
Bremelanotide
Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.
hGHRH(1-37)OH
Human GHRF(1-37)OH has appeared in studies examining how loss of C-terminal residues affects biological activity at the GHRH receptor. It is often used alongside other fragments to define structure-activity relationships within the GHRH family.
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