Arenicin-1 vs Neuropeptide S

Head-to-head comparison of Arenicin-1 (Arenicin-1) and Neuropeptide S (Neuropeptide S) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyArenicin-1Neuropeptide S
CategoryMarine-DerivedCognitive Enhancement
Full NameArenicin-1Neuropeptide S
Molecular Weight2079 Da2203 Da
Half-Lifen/aMinutes to <1 hour
Amino Acids2120
Typical Dosen/aResearch-only; no validated human dose
RoutepreclinicalIntracerebroventricular/Intranasal
Purity≥98%≥98%
Studies Count7628
Research StatusPre-clinicalPre-clinical

Arenicin-1 Benefits

  • antimicrobial
  • anti-biofilm
  • membrane-active

Neuropeptide S Benefits

  • anxiolysis
  • stress resilience
  • attention support
  • arousal modulation

Arenicin-1 Dosing

bacterial infection|biofilm disruption

Neuropeptide S Dosing

0.1-1 nmol i.c.v. in animal studies|intranasal research-only exploration|no established human protocol

Arenicin-1 Side Effects

  • Arenicola marina

Neuropeptide S Side Effects

  • sleep disruption
  • headache
  • jitteriness

Research Overview

Arenicin-1

Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.

Neuropeptide S

Animal studies suggest NPS can reduce anxiety-like behavior while altering wakefulness and alertness through the NPS receptor system. Human cognitive data are very limited, and it has no approved clinical indication.

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Common Stacking Partners

Arenicin-1 stacks with:

Arenicola marinabeta-hairpinantibiotic

Neuropeptide S stacks with:

BromantaneTianeptine sodium
marine-derivedbioactiveantimicrobial peptidebiofilmpeptideanxiolyticstress