5-Amino-1MQ vs Secretin
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and Secretin (Human Secretin) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | Secretin |
|---|---|---|
| Category | Weight Management | Gastrointestinal |
| Full Name | 5-Amino-1-methylquinolinium | Human Secretin |
| Molecular Weight | 178.23 g/mol | 3055.4 Da |
| Half-Life | ~6 hours | 5-7 minutes |
| Amino Acids | Small molecule | 27 |
| Typical Dose | — | 0.2 mcg/kg IV |
| Route | — | Intravenous |
| Purity | >98% | ≥98% |
| Studies Count | 28 | 800 |
| Research Status | Active Research | Clinical |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
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