5-Amino-1MQ vs hGHRH(1-37)OH
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and hGHRH(1-37)OH (Human growth hormone-releasing factor (1-37) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | hGHRH(1-37)OH |
|---|---|---|
| Category | Weight Management | Growth Hormone |
| Full Name | 5-Amino-1-methylquinolinium | Human growth hormone-releasing factor (1-37) hydroxyl |
| Molecular Weight | 178.23 g/mol | N/A |
| Half-Life | ~6 hours | 5-20 minutes |
| Amino Acids | Small molecule | 37 |
| Typical Dose | — | 1-2 mcg/kg |
| Route | — | Subcutaneous/IV |
| Purity | >98% | ≥98% |
| Studies Count | 28 | 60 |
| Research Status | Active Research | Clinical Research |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
hGHRH(1-37)OH Benefits
- ✓GH release studies
- ✓minimal-sequence mapping
- ✓receptor pharmacology
- ✓peptide stability research
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
hGHRH(1-37)OH Dosing
1-2 mcg/kg SC or IV bolus|acute stimulation with serial GH assays|short-course research administration with biomarker monitoring
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
hGHRH(1-37)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient fatigue
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
hGHRH(1-37)OH
Human GHRF(1-37)OH has appeared in studies examining how loss of C-terminal residues affects biological activity at the GHRH receptor. It is often used alongside other fragments to define structure-activity relationships within the GHRH family.
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