REGN1033 vs Methoxy PEG-Epoetin Beta
Head-to-head comparison of REGN1033 (Trevogrumab (REGN1033)) and Methoxy PEG-Epoetin Beta (Methoxy polyethylene glycol-epoetin beta (CERA)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | REGN1033 | Methoxy PEG-Epoetin Beta |
|---|---|---|
| Category | Muscle & Performance | Muscle & Performance |
| Full Name | Trevogrumab (REGN1033) | Methoxy polyethylene glycol-epoetin beta (CERA) |
| Molecular Weight | ~150 kDa | ≈60,000 Da |
| Half-Life | ~2-3 weeks | ~130 h |
| Amino Acids | N/A | 165 |
| Typical Dose | 100-300 mg SC or equivalent trial dosing | 0.6 mcg/kg SC every 2 weeks or 1.2 mcg/kg SC monthly |
| Route | Subcutaneous / Intravenous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 60 | 95 |
| Research Status | Clinical | Clinical |
REGN1033 Benefits
- ✓myostatin blockade
- ✓lean-mass preservation
- ✓muscle hypertrophy support
- ✓catabolic-state countermeasure
Methoxy PEG-Epoetin Beta Benefits
- ✓long-acting erythropoiesis
- ✓stable hemoglobin
- ✓fewer injections
- ✓improved oxygen delivery
REGN1033 Dosing
SC or IV clinical-trial dosing|repeat every 2-4 weeks|dose escalation by study
Methoxy PEG-Epoetin Beta Dosing
0.6 mcg/kg SC every 2 weeks|1.2 mcg/kg SC monthly|Adjust based on hemoglobin
REGN1033 Side Effects
- ⚠injection-site reactions
- ⚠headache
- ⚠fatigue
Methoxy PEG-Epoetin Beta Side Effects
- ⚠hypertension
- ⚠thromboembolism
- ⚠headache
Research Overview
REGN1033
Human and animal studies indicate that myostatin neutralization can increase muscle size, though functional gains are often smaller than mass gains. Trevogrumab is part of the broader literature showing that selective myostatin inhibition can alter body composition in clinically meaningful ways.
Methoxy PEG-Epoetin Beta
Clinical trials show predictable hemoglobin correction with a long dosing interval and sustained red-cell stimulation. Any VO2 max effect would be secondary to higher hemoglobin, not a direct ergogenic mechanism.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.