Thymogen vs Pidotimod
Head-to-head comparison of Thymogen (L-Glutamyl-L-Tryptophan) and Pidotimod (3-L-Pyroglutamyl-L-Thiazolidine-4-Carboxylic Acid) — benefits, dosing, side effects, research data, and where to buy.
| Property | Thymogen | Pidotimod |
|---|---|---|
| Category | Immune Support | Immune Support |
| Full Name | L-Glutamyl-L-Tryptophan | 3-L-Pyroglutamyl-L-Thiazolidine-4-Carboxylic Acid |
| Molecular Weight | 345.34 Da | 244.27 Da |
| Half-Life | 1-2 h | 3-4 h |
| Amino Acids | 2 | 2 |
| Typical Dose | 100-300 mcg | 400-800 mg/day |
| Route | Intranasal | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 60 | 200 |
| Research Status | Clinical | Clinical |
Thymogen Benefits
- ✓cellular-immune-support
- ✓t-cell-signaling
- ✓recovery-adjunct
- ✓infection-resilience
Pidotimod Benefits
- ✓oral-immune-support
- ✓respiratory-infection-adjunct
- ✓innate-immunity
- ✓adaptive-immunity-support
Thymogen Dosing
100-300 mcg/day|intranasal or IM|5-10 day cycles
Pidotimod Dosing
400 mg PO BID|typically 15-30 days|repeated seasonal cycles in studies
Thymogen Side Effects
- ⚠nasal irritation
- ⚠headache
- ⚠hypersensitivity
Pidotimod Side Effects
- ⚠nausea
- ⚠diarrhea
- ⚠rash
Research Overview
Thymogen
Thymogen has been studied as a short thymic peptide-like dipeptide with immunoregulatory activity. The literature focuses on lymphocyte function, cytokine modulation, and use in recurrent respiratory infections or immune suppression states.
Pidotimod
Pidotimod has human data in recurrent infections, especially where immune stimulation or reduced infection frequency is the target. Published work commonly reports improvements in phagocyte function, mucosal defense, and fewer respiratory infection episodes.
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