Secretin vs Bremelanotide
Head-to-head comparison of Secretin (Human Secretin) and Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Secretin | Bremelanotide |
|---|---|---|
| Category | Gastrointestinal | Sexual Health |
| Full Name | Human Secretin | Bremelanotide (PT-141), cyclic melanocortin receptor agonist |
| Molecular Weight | 3055.4 Da | 1025.2 Da |
| Half-Life | 5-7 minutes | about 2.7 h |
| Amino Acids | 27 | 7 |
| Typical Dose | 0.2 mcg/kg IV | 1.75 mg |
| Route | Intravenous | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 800 | 200 |
| Research Status | Clinical | Clinical |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
Bremelanotide Benefits
- ✓increases sexual desire
- ✓supports arousal
- ✓may improve erectile response
- ✓on-demand use
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
Bremelanotide Dosing
1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
Bremelanotide Side Effects
- ⚠nausea
- ⚠flushing
- ⚠headache
- ⚠transient blood pressure increase
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
Bremelanotide
Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.
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