BMP-2 vs P-15
Head-to-head comparison of BMP-2 (Recombinant Human Bone Morphogenetic Protein-2) and P-15 (Synthetic Collagen Type I Cell-Binding Peptide (P-15)) — benefits, dosing, side effects, research data, and where to buy.
| Property | BMP-2 | P-15 |
|---|---|---|
| Category | Recovery & Healing | Recovery & Healing |
| Full Name | Recombinant Human Bone Morphogenetic Protein-2 | Synthetic Collagen Type I Cell-Binding Peptide (P-15) |
| Molecular Weight | 26000 Da | 1500 Da |
| Half-Life | short, localized exposure | N/A |
| Amino Acids | 114 | 15 |
| Typical Dose | 1.5 mg/mL local implant | device-dependent local loading |
| Route | Local/Implant | Local/Implant |
| Purity | ≥98% | ≥98% |
| Studies Count | 1500 | 150 |
| Research Status | Clinical | Clinical |
BMP-2 Benefits
- ✓promotes osteogenesis
- ✓supports nonunion healing
- ✓enhances scaffold-based repair
- ✓may improve defect fill
P-15 Benefits
- ✓improves osteoblast attachment
- ✓supports scaffold osteointegration
- ✓enhances bone fill
- ✓may aid periodontal regeneration
BMP-2 Dosing
local implantation on collagen sponge|single intraoperative dose|procedure-specific scaffold delivery
P-15 Dosing
embedded in scaffold or graft material|local application|single procedural exposure
BMP-2 Side Effects
- ⚠local inflammation
- ⚠ectopic bone formation
- ⚠edema
P-15 Side Effects
- ⚠local irritation
- ⚠inflammation
- ⚠hypersensitivity
Research Overview
BMP-2
rhBMP-2 has strong clinical and translational literature for bone regeneration, spinal fusion, and defect repair. Its use is primarily local because systemic exposure is not the intended mechanism.
P-15
P-15 is a real literature-backed peptide used to improve biomaterial performance in bone repair settings. Most of the evidence is device- or scaffold-based rather than as a free systemic peptide.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.