Omentin-1 vs Irisin
Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and Irisin (Irisin (FNDC5 cleavage product)) — benefits, dosing, side effects, research data, and where to buy.
| Property | Omentin-1 | Irisin |
|---|---|---|
| Category | Diabetes & Metabolic | Diabetes & Metabolic |
| Full Name | Omentin-1 (Intelectin-1, ITLN1) | Irisin (FNDC5 cleavage product) |
| Molecular Weight | ~35 kDa | ~12.3 kDa |
| Half-Life | hours | hours |
| Amino Acids | 313 | 112 |
| Typical Dose | No approved human dose; research use only | No approved human dose; research use only |
| Route | IV|SC | IV|SC |
| Purity | ≥98% | ≥98% |
| Studies Count | 82 | 79 |
| Research Status | Pre-clinical | Pre-clinical |
Omentin-1 Benefits
- ✓insulin sensitivity
- ✓glucose uptake
- ✓lipid handling
Irisin Benefits
- ✓glucose homeostasis
- ✓energy expenditure
- ✓brown-fat activation
Omentin-1 Dosing
not established|not established
Irisin Dosing
not established|not established
Omentin-1 Side Effects
- ⚠unknown
- ⚠immunogenicity risk
Irisin Side Effects
- ⚠unknown
- ⚠immunogenicity risk
Research Overview
Omentin-1
Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.
Irisin
Irisin is widely explored in obesity and type 2 diabetes research because it connects exercise biology with metabolic adaptation. Human findings are mixed, so it remains a biomarker and preclinical lead rather than an approved therapy.
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