Ipamorelin vs CJC-1295
Head-to-head comparison of Ipamorelin (Growth Hormone Secretagogue) and CJC-1295 (Growth Hormone Releasing Hormone Analog) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Ipamorelin | CJC-1295 |
|---|---|---|
| Category | Performance | Performance |
| Full Name | Growth Hormone Secretagogue | Growth Hormone Releasing Hormone Analog |
| Molecular Weight | 711.85 Da | 3,367.97 Da |
| Half-Life | ~2 hours | ~6-8 days (DAC) |
| Amino Acids | 5 | 30 |
| Typical Dose | 200-300 mcg | 1-2 mg/week |
| Route | SC | SC |
| Purity | — | — |
| Studies Count | 156 | 167 |
| Research Status | Clinical Trials | Clinical Trials |
Ipamorelin Benefits
- ✓Stimulates natural GH release
- ✓Minimal cortisol/prolactin increase
- ✓Improved body composition
- ✓Enhanced recovery and sleep quality
- ✓Anti-aging effects
CJC-1295 Benefits
- ✓Sustained GH release over days
- ✓Improved body composition
- ✓Enhanced deep sleep quality
- ✓Accelerated recovery from training
- ✓Increased protein synthesis
Ipamorelin Dosing
Standard: 200-300 mcg SC 2-3 times daily|Pre-bed: 200 mcg SC 30 min before sleep|Combined: 100-200 mcg with CJC-1295 2-3x daily
CJC-1295 Dosing
Without DAC: 100-200 mcg SC 2-3 times daily|With DAC: 1-2 mg SC once or twice weekly|Combined with Ipamorelin: 100 mcg each, 2-3x daily
Ipamorelin Side Effects
- ⚠Common (Mild): Temporary tingling, water retention, increased appetite
- ⚠Rare: Headache, lightheadedness
- ⚠Very Well Tolerated overall
CJC-1295 Side Effects
- ⚠Common (Mild): Water retention, tingling/numbness, flushing
- ⚠Moderate: Joint stiffness, carpal tunnel-like symptoms
- ⚠Rare: Elevated blood sugar (transient)
Research Overview
Ipamorelin
Ipamorelin has moderate clinical evidence. Phase II trials demonstrate selective GH release. Generally regarded as one of the safest GH secretagogues with minimal side effect profile.
CJC-1295
CJC-1295 has good pre-clinical and early clinical data. The DAC variant shows sustained GH elevation for days. Often combined with GHRPs for synergistic GH release.
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