HGH Fragment 176-191 vs Tesofensine
Head-to-head comparison of HGH Fragment 176-191 (Human Growth Hormone Fragment 176-191) and Tesofensine (Tesofensine (NS2330)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | HGH Fragment 176-191 | Tesofensine |
|---|---|---|
| Category | Weight Management | Weight Management |
| Full Name | Human Growth Hormone Fragment 176-191 | Tesofensine (NS2330) |
| Molecular Weight | 1817.12 g/mol | 426.52 g/mol |
| Half-Life | ~30 minutes | ~200-300 hours |
| Amino Acids | 16 | Small molecule |
| Typical Dose | — | — |
| Route | — | — |
| Purity | >98% | >98% |
| Studies Count | 45 | 35 |
| Research Status | Active Research | Phase III Clinical Trials |
HGH Fragment 176-191 Benefits
- ✓Targeted fat loss, no blood sugar impact, no IGF-1 elevation, inhibits lipogenesis, stimulates lipolysis, improved body composition
Tesofensine Benefits
- ✓Potent appetite suppression, increased metabolic rate, enhanced thermogenesis, improved mood during dieting, reduces food reward-seeking behavior
HGH Fragment 176-191 Dosing
250-500 mcg subcutaneously 1-2 times daily on empty stomach. 12-16 week cycles typical in research.
Tesofensine Dosing
Clinical doses: 0.25-1.0 mg orally once daily. Research typically uses 0.5 mg. Extremely long half-life (8-13 days) means steady-state in 7-10 days.
HGH Fragment 176-191 Side Effects
- ⚠Injection site irritation, headache, drowsiness. Does not affect blood sugar, insulin sensitivity, or elevate IGF-1.
Tesofensine Side Effects
- ⚠Dry mouth, insomnia, constipation, increased heart rate, elevated blood pressure. Not recommended with uncontrolled hypertension.
Research Overview
HGH Fragment 176-191
This 16-amino-acid fragment specifically targets adipose tissue via beta-3 adrenergic receptors. Works through a GH-receptor-independent pathway, explaining selective fat-loss properties without growth-promoting effects.
Tesofensine
Phase II trials showed 12.8 kg average weight loss at 1.0 mg dose over 6 months. Simultaneously inhibits reuptake of norepinephrine, dopamine, and serotonin, producing appetite suppression and increased thermogenesis.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.