hGHRH(1-40)OH vs Capromorelin

Head-to-head comparison of hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) and Capromorelin (Capromorelin hydrochloride) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyhGHRH(1-40)OHCapromorelin
CategoryGrowth HormoneGrowth Hormone
Full NameHuman growth hormone-releasing factor (1-40) hydroxylCapromorelin hydrochloride
Molecular WeightN/AN/A
Half-Life5-20 minutesabout 2-3 hours
Amino Acids40N/A
Typical Dose1-2 mcg/kg0.25-2 mg/kg/day
RouteSubcutaneous/IVOral
Purity≥98%≥98%
Studies Count8555
Research StatusClinical ResearchClinical

hGHRH(1-40)OH Benefits

  • GH secretion research
  • fragment-activity comparison
  • receptor binding studies
  • axis physiology modeling

Capromorelin Benefits

  • GH secretagogue activity
  • appetite stimulation
  • oral administration
  • translational animal model utility

hGHRH(1-40)OH Dosing

1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies

Capromorelin Dosing

0.25-2 mg/kg orally in studies|once-daily or protocol-specific dosing|monitor appetite and body weight

hGHRH(1-40)OH Side Effects

  • flushing
  • headache
  • lightheadedness

Capromorelin Side Effects

  • increased appetite
  • vomiting or nausea
  • lethargy

Research Overview

hGHRH(1-40)OH

Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.

Capromorelin

Research consistently shows capromorelin activates the ghrelin receptor pathway and increases food intake. Human development has been less prominent than veterinary use, but the compound remains a relevant GH secretagogue prototype.

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Common Stacking Partners

hGHRH(1-40)OH stacks with:

L-arginineL-ornithineglycine

Capromorelin stacks with:

Nutritional supportResistance training
ghrhfragmentpituitaryresearch-peptideghrelin-receptor-agonistappetite-stimulantgh-secretagogue